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We think that while it is clear that different endpoints may yield quite different results, the human MOE for cannabis based on the endpoint psychotropic effects can be seen as general validation of the MOE concept, because the resulting values below 1 are expected as the psychotropic effect is the desired endpoint (and hence the psychotropic threshold dose is exceeded by drug users)

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Sabrina L

There are over 30 types of TMJ disorders (TMDs), each with their own unique set of symptoms, such as: Ear pain Jaw pain Headaches Sinus pressure Pain in the eye However, all TMDs are characterized by pain in the jaw with a limited range of motion