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These results may be related to Spain and Italy, being Mediterranean countries, having a deeper understanding and research focus on the MedDiet

Nanomed., 2019, 14, 667687 CrossRef

Thus, it is worth exploring whether the development of cuprotosis is indirectly related to ferroptosis

Because exogenous -KG minimally contributes to the TCA cycle because of the lack of a mitochondrial importer 27 , this result suggests that exogenous -KG functions outside of the mitochondrion in shGDH1 cells under this context