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Day 0,3,7 VITdAL-ICU Placebo: Mixed effects regression results of Day 0,3,7 data from the VITdAL-ICU cohort in patients who received Placebo adjusted for age, sex, baseline 25(OH)D, absolute increase in 25(OH)D at day 3, SAPS II, plasma day, admission diagnosis, and an individual subject-specific random-intercept

Compared with the healthy mice, there was a significant increase in the serum levels of MDA, and a significant decrease in the serum levels of SOD and GSH-Px in the mice with cachexia receiving saline