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None of these processes announce themselves with a dramatic color change or obvious warning sign

Yet, one study in 24 healthy volunteers reported no significant drug interactions with the co-administration of a single oral dose of lipoic acid (600 mg) and the oral anti-diabetic agents, glyburide (also called glybenclamide) or acarbose (Precose/Prandase/Glucobay) (119)

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Cut-off values have been established for these biomarkers, but although they may help physicians identify the most appropriate time to start treatment for kidney damage, no corresponding treatment exists (84)