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F.LoiblS.MunsterP.BruzzoneM.et al (2018)

Accumulation and aggregation of neurotoxic proteins, such as -amyloid (A), hyperphosphorylated tau, ubiquitinated proteins, and other unfolded proteins in vulnerable brain regions such as the hippocampus and cortex in AD brain is central to disease pathogenesis (Selkoe, 2001)

Tissues and structures affected by knee OA include: The articular cartilage, a smooth surface covering the bones that reduces friction and serves as a shock absorber gradually breaks down and erodes

- Diminishes skin pigmentation, addressing concerns like melasma, scars, adverse chemical peel effects, and chickenpox