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By managing these client proteins, HSP70s function in two principal modes: facilitating the proper folding of nascent and partially denatured proteins or targeting abnormal and irreversibly damaged proteins for degradation and clearance, a process known as protein quality control (PQC) (Yan et al., 2020)

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44 The controlled release of drugs from microspheres depends on the rate of degradation and is regulated by the internal monomer ratio or molecular weight