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The technique of isobaric tags for relative and absolute quantification (iTRAQ) allows unambiguous identification and quantification of proteins expressed in a complex tissue matrix and presents here a snapshot of the hepatoproteome at each of the time-points examined

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Notably, more than 95% of Kupffer cells expressed TIM4, a marker of embryonically-derived Kupffer cells 25 , indicating that repopulation by monocyte-derived macrophages (which are typically TIM4 ) was minimal under these conditions (Supplementary Fig

The reason why homocysteine is dangerous is because it damages cells and tissues of the arteries, triggers inflammatory reactions and enables cholesterol oxidation, which contributes to the build-up of atherosclerotic plaques the main culprits in cardiovascular disease (Kumar et al., 2017)