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The molecular mechanisms and precise roles of ferroptosis in chronic kidney diseases, such as renal fibrosis, diabetic kidney disease and polycystic kidney disease, need further investigation

G protein-coupled receptors (GPCRs), also called seven-(pass)-transmembrane domain receptors, seven-(pass)-transmembrane domain receptors, heptahelical receptors, serpentine receptors, and G protein-linked receptors (GPLR), are a large family of evolutionarily related proteins that are cell surface receptors that recognize molecules outside the cell and trigger cellular responses

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Comment This is a rare condition in rats but is a more common age-related phenomenon in hamsters and mice (Greaves 2007