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It gets into circulation, where it can reach follicles from the blood supply as well as exert broader systemic effects

When to decrease dose Consider decreasing if: Persistent side effects that don't resolve Excellent results achieved and maintenance desired Budget constraints require conservation Stacking and wanting to optimize ratios Many researchers find they can reduce dose during maintenance phases after achieving initial goals during more intensive loading phases

Weeks 1 to 2: initial phase During the first two weeks, most users notice subtle improvements in skin hydration and texture

The decrease in activity causes fewer amounts of hormones and peptides to be produced by the thymus