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The rationale is that glucagon also increases energy expenditure and promotes hepatic fat mobilization, so a molecule that combines glucagons metabolic-rate effect with GLP-1/GIPs appetite-and-glucose control can, in principle, drive weight loss from both sides of the energy-balance equation at once

But the core insight holds: the brain runs substantially on peptide signals, and that makes peptides a legitimate place to look for cognitive leverage

Celastrol Inhibits Dopaminergic Neuronal Death of Parkinsons Disease through Activating Mitophagy

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