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Always stretch gently and avoid forcing the movement, as aggressive stretching can worsen the cramp or cause injury

Similarly, intestine-specific Znt10 KO revealed moderate systemic Mn accumulation, whereas intestine and liver double Znt10 KO resulted in severe Mn overload compared to either KO alone (Mercadante et al., 2019), suggesting that both intestine and liver ZNT10 play an essential role in Mn excretion