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3.4.1 Protective effects of metformin on cardiovascular disease risk in patients with polycystic ovary syndrome Epidemiological research suggests that individuals with PCOS exhibit a greater prevalence of hypertension compared to those without PCOS, particularly among females of reproductive age, and their cardiovascular risk is notably elevated irrespective of their BMI

Commonly Reported Effects The most frequently mentioned side effect is next-morning fatigue or grogginess, typically reported when doses exceed individual tolerance or timing is off

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